Mouse cerebellum, chick spinal cord, and chick retina that categorical the E type of N-CAM were dissected and cultured on collagen gels. After 3-6 d in culture, elevated proportions of A forms had been synthesized, as revealed by specific immunoprecipitation and immunoblotting. The rate of E-to-A conversion and the proportions of the totally different A forms synthesized in vitro had been much like those...